Fructose and high fructose corn syrup: are they a two-edged sword?

Int J Food Sci Nutr. 2021 Aug;72(5):592-614. doi: 10.1080/09637486.2020.1862068. Epub 2021 Jan 26.

Abstract

High-fructose syrups are used as sugar substitutes due to their physical and functional properties. High fructose corn syrup (HFCS) is used in bakery products, dairy products, breakfast cereals and beverages, but it has been reported that there might be a direct relationship between high fructose intake and adverse health effects such as obesity and the metabolic syndrome. Thus, fructose has recently received much attention, most of which was negative. Although studies have indicated that there might be a correlation between high fructose-rich diet and several adverse effects, however, the results of these studies cannot be certainly generalised to the effects of HFCS; because they have investigated pure fructose at very high concentrations in measurement of metabolic upsets. This review critically considered the advantages and possible disadvantages of HFCS application and consumption in food industry, as a current challenging issue between nutritionists and food technologists.

Keywords: Sweetener; beverage; foods; health; high fructose corn syrup (HFCS).

Publication types

  • Review

MeSH terms

  • Beverages
  • Fructose* / adverse effects
  • High Fructose Corn Syrup* / adverse effects
  • Humans
  • Metabolic Syndrome / etiology
  • Obesity / etiology
  • Sweetening Agents* / adverse effects

Substances

  • High Fructose Corn Syrup
  • Sweetening Agents
  • Fructose