High-intensity focused ultrasound treatment as an alternative regimen for myxofibrosarcoma

Dermatol Ther. 2021 Mar;34(2):e14816. doi: 10.1111/dth.14816. Epub 2021 Feb 4.

Abstract

Myxofibrosarcoma is a common soft-tissue sarcoma in elderly patients, characterized by an infiltrative growth pattern and a high risk for persistent local recurrence. A 35-years-old woman was diagnosed with myxofibrosarcoma on the right upper arm and the tumor is surgically resected. The tumor relapsed 7 months later. Then the patient received five cycles of low power cumulative high-intensity focused ultrasound (HIFU) treatments, which completely ablated the tumor without complications. Now the patient is disease free with a high quality of life more than 30 months. This case indicates HIFU ablation might be a novel, promising therapy for recurrent myxofibrosarcoma.

Keywords: fibrosarcoma; high-intensity focused ultrasound ablation; local; neoplasm recurrence.

MeSH terms

  • Adult
  • Aged
  • Female
  • Fibrosarcoma* / therapy
  • High-Intensity Focused Ultrasound Ablation* / adverse effects
  • Humans
  • Neoplasm Recurrence, Local
  • Quality of Life
  • Soft Tissue Neoplasms* / therapy