COVID-19 in Children with Asthma

Lung. 2021 Feb;199(1):7-12. doi: 10.1007/s00408-021-00419-9. Epub 2021 Jan 26.

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects both children and adults but epidemiological and clinical data demonstrate that children are less likely to have a severe disease course or die. Furthermore, asthmatic children show less severe disease manifestations when infected with SARS-CoV-2 comparing to adults. This review focuses on SARS-CoV-2 and childhood asthma interaction and aims at summarizing the current knowledge of the potential mechanisms that ameliorate disease symptomatology in asthmatic children.

Keywords: Asthma; COVID-19; Children; SARS-CoV-2.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Asthma* / epidemiology
  • Asthma* / immunology
  • Asymptomatic Diseases
  • COVID-19 / immunology
  • COVID-19 / mortality
  • COVID-19 / virology*
  • Child
  • Female
  • Host-Pathogen Interactions
  • Humans
  • Male
  • Prognosis
  • Protective Factors
  • Risk Factors
  • SARS-CoV-2 / immunology
  • SARS-CoV-2 / pathogenicity*
  • Severity of Illness Index