Coccidioidomycosis: a review

J Investig Med. 2021 Feb;69(2):316-323. doi: 10.1136/jim-2020-001655.

Abstract

Coccidioidomycosis is a fungal infection of the Western hemisphere that is endemic to the soil in areas with limited rainfall. Human and animal infections result with inhalation of arthroconidia. Most often, this is an asymptomatic event. When illness occurs, it is primarily a pneumonic presentation. A small minority of infections eventuate in disseminated disease. Predominately, this presents as meningitis or osteoarticular or integumentary disease. Treatment may not be required for the mildest illness. Azoles are commonly prescribed. Severe infections may require amphotericin B.

Keywords: pneumonia; publishing.

Publication types

  • Review

MeSH terms

  • Animals
  • Antifungal Agents / therapeutic use
  • Coccidioidomycosis* / diagnosis
  • Coccidioidomycosis* / drug therapy
  • Coccidioidomycosis* / epidemiology
  • Humans

Substances

  • Antifungal Agents