Recruiting in intervention studies: challenges and solutions

BMJ Open. 2021 Jan 25;11(1):e044702. doi: 10.1136/bmjopen-2020-044702.

Abstract

Introduction: In order for study results to be relevant for practice, the study participants should represent the source population. A common problem is recruitment of sufficient and representative subjects, threatening the external validity of the study and, ultimately, evidence-based practice. The aim was to highlight common challenges and to present possible solutions to recruitment.

Methods: Using four recent randomised controlled trials as examples, common recruitment challenges were highlighted and solutions were proposed. The four studies represented some common and some specific challenges, but they investigated interventions for the prevention of the two major public health challenges of today: musculoskeletal pain and common mental disorders.

Results: Identified challenges and suggested solutions were presented as a checklist to be used for future trials in order to aid recruitment and reporting thereof.

Keywords: epidemiology; primary care; public health.

MeSH terms

  • Humans
  • Mental Disorders* / therapy
  • Patient Selection