False-Positive Uptake of 131I From Basal Cell Papilloma in a Patient With Metastatic Papillary Thyroid Cancer

Clin Nucl Med. 2021 Apr 1;46(4):358-360. doi: 10.1097/RLU.0000000000003506.

Abstract

A 64-year-old woman with metastatic papillary thyroid cancer underwent a total thyroidectomy followed by 2 courses of 131I therapy. The posttherapeutic whole-body scan after the second dose of 131I therapy showed multifocal bone metastasis. In addition, there is focal abnormal intense radiotracer uptake at the right inguinal region. SPECT/CT revealed that this abnormal focal radioactivity was from a superficial skin lesion. Further physical examination revealed a raised, approximately 1-cm, irregular grayish-brown lesion on the right groin skin. Histopathological examination confirmed the diagnosis of basal cell papilloma (seborrheic keratosis).

Publication types

  • Case Reports

MeSH terms

  • False Positive Reactions
  • Female
  • Humans
  • Iodine Radioisotopes / metabolism*
  • Middle Aged
  • Neoplasms, Basal Cell / diagnostic imaging
  • Neoplasms, Basal Cell / metabolism*
  • Neoplasms, Basal Cell / secondary*
  • Papilloma / diagnostic imaging
  • Papilloma / metabolism*
  • Single Photon Emission Computed Tomography Computed Tomography
  • Thyroid Cancer, Papillary / pathology*
  • Thyroidectomy
  • Whole Body Imaging

Substances

  • Iodine Radioisotopes
  • Iodine-131