Continuous positive airway pressure (CPAP) is an effective treatment modality for patients with obstructive sleep apnoea syndrome (OSAS). Surgical treatment of OSAS can include functional nasal surgery, uvulopalatopharyngoplasty, transoral robotic surgery, maxillo-mandibular advancement (MMA) and bariatric surgery. MMA should be considered in patients with moderate to severe OSAS, if CPAP treatment is ineffective or not tolerated, as well in patients with failure of previous sleep surgery or in patients with severe dentofacial anomalies. In this review, we stress, that multidisciplinary management between sleep medicine clinicians and surgeons is crucial.