A dataset of four probiotic Bifidobacterium strains genome assemblies

Aleksei A Korzhenkov; Alina V Tepliuk; Konstantin V Sidoruk; Konstantin E Voyushin; Maksim V Patrushev; Ilya V Kublanov; Stepan V Toshchakov

doi:10.1016/j.dib.2020.106710

A dataset of four probiotic Bifidobacterium strains genome assemblies

Data Brief. 2020 Dec 31:34:106710. doi: 10.1016/j.dib.2020.106710. eCollection 2021 Feb.

Authors

Aleksei A Korzhenkov¹, Alina V Tepliuk^{1

2}, Konstantin V Sidoruk³, Konstantin E Voyushin³, Maksim V Patrushev¹, Ilya V Kublanov⁴, Stepan V Toshchakov¹

Affiliations

¹ National Research Center "Kurchatov Institute", Moscow, Russia.
² Albiogen, Moscow, Russia.
³ Federal Institution "State Research Institute of Genetics and Selection of Industrial Microorganisms" of the National Research Center "Kurchatov Institute", Moscow, Russia.
⁴ Winogradsky Institute of Microbiology, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

Abstract

A dataset of four draft genome sequences of Bifidobacterium strains is presented. All four genome assemblies are high-quality drafts characterized by high completeness and low contamination levels. GC content of the genomes varied in the range between 59.27% and 62.77%. Genome sequences were annotated for further functional and taxonomical analyses of the respective Bifidobacterium strains. Genetic determinants of probiotic capabilities, including the genes, related to utilization of human milk oligosaccharides and mucin, as well as the genes, encoding bile salt hydrolase were identified. The genome of B. bifidum VKPM=Ac-1784 has been shown to possess two bacteriocin gene clusters. The dataset expands knowledge on genomic diversity of probiotic strains of Bifidobacterium genus. The dataset is available under PRJNA656137 accession number in NCBI database and under zyv26t6x5r accession number in Mendeley Data repository.

Keywords: Bacteriocins; Bifidobacteria; Human milk oligosaccharides; Microbial genomics; Probiotics.