Empagliflozin-Associated Pancreatitis: A Consideration for SGLT2 Inhibitors

ACG Case Rep J. 2021 Jan 19;8(1):e00530. doi: 10.14309/crj.0000000000000530. eCollection 2021 Jan.

Abstract

Empagliflozin belongs to a class of sodium-glucose cotransporter-2 inhibitors, a medication approved by the US Food and Drug Administration in 2014 for the treatment of type 2 diabetes mellitus. Well-known side effects of this medication include symptomatic hypotension, hypoglycemia, and urinary tract infections among others. We present a case of severe epigastric abdominal pain consistent with acute pancreatitis in the setting of empagliflozin use, suggesting a possible drug-induced acute pancreatitis.

Publication types

  • Case Reports