Peritoneal dissemination of breast cancer diagnosed by laparoscopy

Tsuyoshi Nakagawa; Goshi Oda; Akifumi Kikuchi; Toshifumi Saito; Tomoyuki Fujioka; Kazunori Kubota; Mio Mori; Iichiro Onishi; Hiroyuki Uetake

doi:10.1007/s13691-020-00456-w

Peritoneal dissemination of breast cancer diagnosed by laparoscopy

Int Cancer Conf J. 2020 Nov 14;10(1):91-94. doi: 10.1007/s13691-020-00456-w. eCollection 2021 Jan.

Authors

Tsuyoshi Nakagawa¹, Goshi Oda¹, Akifumi Kikuchi², Toshifumi Saito², Tomoyuki Fujioka³, Kazunori Kubota³, Mio Mori³, Iichiro Onishi⁴, Hiroyuki Uetake¹

Affiliations

¹ Department of Breast Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima Bunkyou-ku, Tokyo, 113-8519 Japan.
² Department of Colorectal Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
³ Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
⁴ Department of Pathology, Tokyo Medical and Dental University, Tokyo, Japan.

Abstract

The accuracy of modern imaging techniques for the diagnosis of peritoneal carcinomatosis is poor. A breast cancer patient with a high serum CA15-3 level did not receive a definitive diagnosis of peritoneal dissemination by imaging examination and then underwent laparoscopy. Pathological examination showed peritoneal dissemination of breast cancer, but the biological markers were different from the primary lesion: ER(-), PgR(-), and Her2:3 +. T-DM1 therapy was very effective, and her systemic symptoms disappeared. Since biomarkers of metastatic lesions may sometimes change, laparoscopic biopsy is very important and useful.

Keywords: Breast cancer; Laparoscopy; Peritoneal dissemination.