Thymoangiolipoma: A rare histologic variant of thymolipoma in a patient with myasthenia gravis

Mohammad Hossein Anbardar; Fatemeh Amirmoezi; Armin Amirian

doi:10.1177/2036361320979215

Thymoangiolipoma: A rare histologic variant of thymolipoma in a patient with myasthenia gravis

Rare Tumors. 2020 Dec 24:12:2036361320979215. doi: 10.1177/2036361320979215. eCollection 2020.

Authors

Mohammad Hossein Anbardar¹, Fatemeh Amirmoezi², Armin Amirian³

Affiliations

¹ Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
² Student Research Committee, Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
³ Department of Surgery, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

Thymoangiolipoma is a rare, slow-growing, benign thymic neoplasm that arises from the anterior mediastinum. A 61-year-old man with the chief complaint of right eye ptosis and high serum acetylcholine receptor antibody level is presented here. The spiral computed tomography of the chest revealed a hypodense mass in the anterior mediastinum. Microscopic examination showed admixture of adipose tissue, thymic tissue and blood vessels with the diagnosis of thymoangiolipoma. Thymoangiolipoma is a rare histologic variant of thymolipoma which can be associated with myasthenia gravis and must be considered as a differential diagnosis in anterior mediastinal mass with fat density in radiologic evaluation.

Keywords: Thymus; histopathology; mediastinum; thymoangiolipoma; thymolipoma.

Publication types

Case Reports