Subclinical Myocarditis After Combination Immune Checkpoint Inhibitor Therapy

Circ Heart Fail. 2021 Feb;14(2):e007524. doi: 10.1161/CIRCHEARTFAILURE.120.007524. Epub 2021 Jan 22.

Affiliations

¹ Department of Cardiology (G.T.G., L.M., E.J.), Mater Misericordiae University Hospital, Dublin, Ireland.
² Department of Medical Oncology (C.D., H.F., R.C., C.M.K.), Mater Misericordiae University Hospital, Dublin, Ireland.
³ Department of Histopathology (D.T., C.O.K., N.M.), Mater Misericordiae University Hospital, Dublin, Ireland.

PMID: 33478241
DOI: 10.1161/CIRCHEARTFAILURE.120.007524

No abstract available

Keywords: gadolinium; magnetic resonance imaging; melanoma; myocarditis; troponin.

Publication types

Case Reports

MeSH terms

Autoimmune Diseases / chemically induced*
Autoimmune Diseases / diagnostic imaging
Autoimmune Diseases / drug therapy
Autoimmune Diseases / pathology
CD8-Positive T-Lymphocytes / pathology
Dermatitis / etiology
Diarrhea / chemically induced
Echocardiography
Female
Glucocorticoids / therapeutic use
Humans
Immune Checkpoint Inhibitors / adverse effects*
Immunoglobulins, Intravenous / therapeutic use
Immunologic Factors / therapeutic use
Ipilimumab / adverse effects*
Lymph Nodes / pathology
Lymphatic Metastasis
Magnetic Resonance Imaging
Melanoma / drug therapy*
Melanoma / secondary
Middle Aged
Myocarditis / chemically induced*
Myocarditis / diagnostic imaging
Myocarditis / drug therapy
Myocarditis / pathology
Natriuretic Peptide, Brain / blood
Nivolumab / adverse effects*
Skin Neoplasms / pathology*
Telemetry
Thyroiditis / chemically induced
Troponin I / blood

Substances

Glucocorticoids
Immune Checkpoint Inhibitors
Immunoglobulins, Intravenous
Immunologic Factors
Ipilimumab
Troponin I
Natriuretic Peptide, Brain
Nivolumab