Integrating pharmacogenetic testing via medication therapy management in an outpatient family medicine clinic

Pharmacogenomics. 2021 Mar;22(4):203-212. doi: 10.2217/pgs-2020-0178. Epub 2021 Jan 20.

Abstract

Introduction: Pharmacogenetic (PGx) implementation has lagged behind the development of drug/gene pair guidelines. Materials & methods: This was a prospective study assessing the integration of PGx through medication therapy management in an outpatient clinic. Variables collected included patient diagnosis, current medications, failed or discontinued medications, PGx results/recommendations, turnaround time and pre/post clinical ratings. Results: A total of 91 participants completed study procedures with an average enrollment of approximately one consult per week. Participants were referred for testing primarily for guidance for current and future medications. The average number of recommendations per participant was 0.93. Conclusion: Integrating PGx testing into medication therapy management is feasible with PGx results available in under a week resulting in clinical recommendations in over half of patients tested.

Keywords: medication therapy management; outpatient; pharmacogenetics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Care Facilities / organization & administration*
  • Family Practice
  • Female
  • Humans
  • Male
  • Medication Therapy Management*
  • Middle Aged
  • Outpatients
  • Pharmacogenetics
  • Pharmacogenomic Testing / methods*
  • Referral and Consultation
  • Treatment Failure
  • Treatment Outcome
  • Young Adult