Using Glissonian sheath as an alternative way to prevent biliary stricture in living-donor liver transplantation

Asian J Surg. 2021 May;44(5):742-748. doi: 10.1016/j.asjsur.2020.12.032. Epub 2021 Jan 16.

Abstract

Background: /Objective: The aim of this study was to report a single-institution experience involving a Glissonian sheath-to-duct method for biliary reconstruction in living donor liver transplantation, focusing on the association between surgical techniques and biliary stricture rates.

Methods: Three hundred and twenty adult right lobar living donor liver transplantation procedures were analyzed through a comparison of 200 Glissonian sheath-to-duct (GD) reconstructions and 120 duct-to-duct (DD) reconstructions in biliary anastomosis.

Results: At a mean follow-up period of 60.8 months, the GD group had a significantly lower biliary stricture rate (13.5%, 27/200) than the DD group (26.7%, 32/120) (p = 0.003). In biliary anastomosis with single duct anastomosis, the incidence of biliary stricture was significantly greater for the DD group (17/79, 21.5%) than for the GD group (14/141, 9.9%) (p = 0.018).

Conclusion: This study has shown that GD anastomosis of the bile duct produced outstanding results with respect to the reduction of biliary stricture. The GD technique can therefore be suggested as an alternative method for biliary reconstruction in LDLT.

Keywords: Bile duct anastomosis; Biliary stricture; Glissonian sheath; Living donor liver transplantation.

MeSH terms

  • Adult
  • Anastomosis, Surgical
  • Bile Ducts / surgery
  • Constriction, Pathologic / prevention & control
  • Constriction, Pathologic / surgery
  • Humans
  • Liver Transplantation*
  • Living Donors*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / prevention & control