Chromatographic Methods for the Determination of Polyfunctional Amines and Related Compounds Used as Monomers and Additives in Food Packaging Materials: A State-of-the-Art Review

Rafael Paseiro-Cerrato; Ana Rodríguez-Bernaldo De Quirós; Raquel Sendón; Juana Bustos; María Isabel Santillana; José Manuel Cruz; Perfecto Paseiro-Losada

doi:10.1111/j.1541-4337.2010.00133.x

Chromatographic Methods for the Determination of Polyfunctional Amines and Related Compounds Used as Monomers and Additives in Food Packaging Materials: A State-of-the-Art Review

Compr Rev Food Sci Food Saf. 2010 Nov;9(6):676-694. doi: 10.1111/j.1541-4337.2010.00133.x.

Authors

Rafael Paseiro-Cerrato¹, Ana Rodríguez-Bernaldo De Quirós¹, Raquel Sendón¹, Juana Bustos¹, María Isabel Santillana¹, José Manuel Cruz¹, Perfecto Paseiro-Losada¹

Affiliation

¹ Authors Paseiro-Cerrato, de Quirós, Sendón, and Paseiro-Losada are with Dept. of Analytical Chemistry, Nutrition and Food Science, Faculty of Pharmacy, Univ. of Santiago de Compostela, 15782 Santiago de Compostela, Spain. Authors Bustos and Santillana are with Natl. Center for Food, Spanish Agency for Food Safety and Nutrition, 28.220 Majadahonda, Spain. Author Cruz is with Dept. of Chemical Engineering, E.T.S.E.I. Univ. of Vigo, Spain. Direct inquiries to author Paseiro-Losada (E-mail: perfecto.paseiro@usc.es).

PMID: 33467824
DOI: 10.1111/j.1541-4337.2010.00133.x

Abstract

Polyfunctional amines are a group of substances commonly used as additives or monomers in food-contact materials. These substances can migrate into foodstuffs and, consequently, may be potentially dangerous for human health. Due to their different chemical structures and physicochemical properties there does not exist a standard method to analyze polyfunctional amines. This review aims to provide an update on the chromatographic methods used for the determination of polyfunctional amines that are commonly used in the manufacture of food packaging materials. Detailed information regarding chromatographic conditions (mobile phases, chromatographic columns, detection systems, and so on) is provided. Moreover, chemical structures and physicochemical properties of the substances studied are also presented.