[Deep brain stimulation for Parkinson's disease]

Fortschr Neurol Psychiatr. 2021 Jan;89(1-02):56-65. doi: 10.1055/a-1260-0401. Epub 2021 Jan 19.
[Article in German]

Abstract

Deep brain stimulation is an established and evidence-based therapeutic option for the treatment of advanced Parkinson's disease. Main indication and inclusion criteria are the presence of idiopathic Parkinsonism with motor fluctuations and / or dyskinesias and / or with medication refractory tremor, a significant improvement of akinesia / rigidity in response to dopaminergic medication, the absence of relevant cognitive deficits and other significant comorbidities. DBS neurosurgery has a low risk of complications. The clinical programming should follow an established monopolar review algorithm. Regular follow-up visits are required for stimulation monitoring.

Die tiefe Hirnstimulation ist eine etablierte und evidenzbasierte Therapieoption für die Behandlung des fortgeschrittenen Morbus Parkinson. Es handelt sich um eine symptomatische Behandlung mit dem primären Ziel, die Lebensqualität des Patienten zu verbessern. Der operative Eingriff gilt als relativ komplikationsarm.

MeSH terms

  • Deep Brain Stimulation*
  • Dyskinesias*
  • Humans
  • Parkinson Disease* / therapy
  • Treatment Outcome
  • Tremor / therapy