Bougainvinones NP, three new flavonoids from Bougainvillea spectabilis

Fitoterapia. 2021 Mar:149:104832. doi: 10.1016/j.fitote.2021.104832. Epub 2021 Jan 16.

Abstract

In an effort to identify natural bioactive compounds, three new flavonoids (1-3) and six known compounds (4-9) were isolated from the stem bark of Bougainvillea spectabilis. The structures of these compounds were accomplished using comprehensive spectroscopic methods, including 1D and 2D NMR spectra with references to the literatures, as well as high-resolution mass spectrometric analysis. Their cytotoxicity against KB and HeLa S-3 cell lines was also evaluated.

Keywords: Bougainvillea spectabilis; Bougainvinones N-P; Cytotoxicity; Flavonoid; Nyctaginaceae.

MeSH terms

  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cell Line, Tumor
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology*
  • HeLa Cells
  • Humans
  • Molecular Structure
  • Nyctaginaceae / chemistry*
  • Phytochemicals / isolation & purification
  • Phytochemicals / pharmacology
  • Plant Bark / chemistry
  • Vietnam

Substances

  • Antineoplastic Agents, Phytogenic
  • Flavonoids
  • Phytochemicals