Inferior vena cava-syndrome

Vasa. 2021 Jul;50(4):250-264. doi: 10.1024/0301-1526/a000919. Epub 2021 Jan 18.

Abstract

Inferior vena cava syndrome (IVCS) is caused by agenesis, compression, invasion, or thrombosis of the IVC, or may be associated with Budd-Chiari syndrome. Its incidence and prevalence are unknown. Benign IVCS is separated from malignant IVCS. Both cover a wide clinical spectrum reaching from asymptomatic to highly symptomatic cases correlated to the underlying cause, the acuity, the extent of the venous obstruction, and the recruitment and development of venous collateral circuits. Imaging is necessary to determine the underlying cause of IVCS and to guide clinical decisions. Interventional therapy has changed the therapeutic approach in symptomatic patients. This article provides an overview over IVCS and focuses on interventional therapeutic methods and results.

Keywords: Budd-Chiari syndrome; Inferior vena cava syndrome; catheter-directed thrombolysis; inferior vena cava thrombosis; thrombaspiration; tumor compression; venous stenting.

Publication types

  • Review

MeSH terms

  • Budd-Chiari Syndrome*
  • Humans
  • Thrombosis*
  • Vena Cava, Inferior