An Eminent Absence: Agenesis of Inferior Vena Cava Underlying Bilateral Iliac Vein Thrombosis

Giorgia Protti; Fabrizio Elia; Francesca Bosco; Franco Aprà

doi:10.12890/2020_001999

An Eminent Absence: Agenesis of Inferior Vena Cava Underlying Bilateral Iliac Vein Thrombosis

Eur J Case Rep Intern Med. 2020 Oct 22;7(12):001999. doi: 10.12890/2020_001999. eCollection 2020.

Authors

Giorgia Protti¹, Fabrizio Elia¹, Francesca Bosco¹, Franco Aprà¹

Affiliation

¹ High Dependency Unit, San Giovanni Bosco Hospital, Torino, Italy.

Abstract

Among thrombophilic risk factors for deep venous thrombosis (DVT), agenesis of the inferior vena cava (AIVC) is very rare, but it must be considered in specific settings. Here, we present the case of an 18-year-old woman who was admitted to the Emergency Department with swelling and pain of her left leg. Clinical examination and ultrasonography detected extensive proximal DVT of the left leg. After attempted mechanical thrombectomy failed, an abdominal CT scan was obtained, which demonstrated bilateral thrombosis of the iliac-femoral axis in the context of congenital AIVC.

Learning points: Agenesis of the inferior vena cava is a rare risk factor for deep venous thrombosis.Agenesis of the inferior vena cava requires lifetime follow-up and treatment.Idiopathic deep venous thrombosis, especially in young patients, requires additional diagnostic investigation that considers congenital anomalies.

Keywords: Inferior vena cava; agenesis; deep venous thrombosis; thrombophilia.