Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network

Emmanuelle Bompas; Valentine Martin; Fatima Meniai; Maud Toulmonde; Perrine Marec-Berard; Line Claude; Françoise Ducimetiere; Cyrus Chargari; Véronique Minard-Colin; Nadège Corradini; Valérie Laurence; Sophie Piperno-Neumann; Anne-Sophie Defachelles; Valérie Bernier; Antoine Italiano; Daniel Orbach; Jean-Yves Blay; Nathalie Gaspar; Pablo Berlanga

doi:10.1016/j.bulcan.2020.10.009

Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network

Bull Cancer. 2021 Feb;108(2):163-176. doi: 10.1016/j.bulcan.2020.10.009. Epub 2021 Jan 14.

Authors

Emmanuelle Bompas¹, Valentine Martin², Fatima Meniai³, Maud Toulmonde⁴, Perrine Marec-Berard⁵, Line Claude⁶, Françoise Ducimetiere⁷, Cyrus Chargari², Véronique Minard-Colin⁸, Nadège Corradini⁵, Valérie Laurence⁹, Sophie Piperno-Neumann⁹, Anne-Sophie Defachelles¹⁰, Valérie Bernier¹¹, Antoine Italiano¹², Daniel Orbach¹³, Jean-Yves Blay¹⁴, Nathalie Gaspar⁸, Pablo Berlanga¹⁵

Affiliations

¹ Centre René Gauducheau, Medical Oncology Department, Saint-Herblain, France.
² Department of Radiation Oncology, Gustave Roussy, Villejuif, France.
³ University Lille, Inserm, U1189 - ONCO-THAI - Assisted Laser Therapy and Immunotherapy for Oncology, 59000 Lille, France.
⁴ Institut Bergonié, Medical Oncology Department, Bordeaux, France.
⁵ Centre Léon Bérard, Department of Pediatric Oncology, Lyon, France.
⁶ Centre Léon Bérard, Department of radiotherapy, Lyon, France.
⁷ Cancer centre Léon Bérard, Santé-Individu-société EA-INSERM 4129, Lyon, France.
⁸ Department of Pediatric and Adolescent Oncology, Gustave Roussy, Villejuif, France.
⁹ Institut Curie, Medical Oncology Department, Paris, France.
¹⁰ Centre Oscar Lambret, Department of Pediatric Oncology, Lille, France.
¹¹ Oncology Radiotherapy Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
¹² Medical Oncology Department, Gustave Roussy, Villejuif, France.
¹³ Department of Pediatric Oncology, Institut Curie, Paris, France.
¹⁴ Medical Oncology Department, Centre Léon-Bérard, Lyon, France.
¹⁵ Department of Pediatric and Adolescent Oncology, Gustave Roussy, Villejuif, France. Electronic address: pablo.berlanga@gustaveroussy.fr.

PMID: 33455736
DOI: 10.1016/j.bulcan.2020.10.009

Abstract

Sarcomas are a rare heterogeneous group of malignant neoplasms that can arise in almost any anatomic site and any age. Close collaboration among adult and pediatric cancer specialists in the management of these tumors is of foremost importance. In this review, we present the current multidisciplinary organization in care of patients with sarcoma in France and we review the main advances made in the last decades in systemic and radiotherapy treatment in the main sarcoma types diagnosed in children, adolescents and young adults (AYA), thanks to the international collaboration.

Keywords: AYA; Adults; Bone sarcoma; Children; Soft tissue sarcoma.

Publication types

Review

MeSH terms

Adolescent
Adult
Age Factors
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Neoplasms / therapy*
Cancer Care Facilities* / organization & administration
Cancer Care Facilities* / supply & distribution
Child
Community Networks / organization & administration
Community Networks / supply & distribution
Europe
France
Humans
International Cooperation
Lung Neoplasms / radiotherapy
Lung Neoplasms / secondary
Maintenance Chemotherapy
Medical Oncology
Middle Aged
Neoplasm Recurrence, Local / radiotherapy
Neoplasms, Germ Cell and Embryonal / therapy
Osteosarcoma / therapy
Patient Care Team / organization & administration*
Radiotherapy Dosage
Randomized Controlled Trials as Topic
Rhabdomyosarcoma / therapy
Sarcoma / therapy*
Sarcoma, Alveolar Soft Part / therapy
Sarcoma, Ewing / therapy
Societies, Medical
Soft Tissue Neoplasms / therapy*
Young Adult