Imaging data in COVID-19 patients: focused on echocardiographic findings

Int J Cardiovasc Imaging. 2021 May;37(5):1629-1636. doi: 10.1007/s10554-020-02148-1. Epub 2021 Jan 16.

Abstract

To assess imaging data in COVID-19 patients and its association with clinical course and survival and 86 consecutive patients (52 males, 34 females, mean age = 58.8 year) with documented COVID-19 infection were included. Seventy-eight patients (91%) were in severe stage of the disease. All patients underwent transthoracic echocardiography. Mean LVEF was 48.1% and mean estimated systolic pulmonary artery pressure (sPAP) was 27.9 mmHg. LV diastolic dysfunction was mildly abnormal in 49 patients (57.6%) and moderately abnormal in 7 cases (8.2%). Pericardial effusion was present in 5/86 (minimal in size in 3 cases and mild- moderate in 2). In 32/86 cases (37.2%), the severity of infection progressed from "severe" to "critical". Eleven patients (12.8%) died. sPAP and computed tomography score were associated with disease progression (P value = 0.002, 0.002 respectively). Tricuspid annular plane systolic excursion (TAPSE) was significantly higher in patients with no disease progression compared with those who deteriorated (P value = 0.005). Pericardial effusion (minimal, mild or moderate) was detected more often in progressive disease (P = 0.03). sPAP was significantly lower among survivors (P value = 0.007). Echocardiographic findings (including systolic PAP, TAPSE and pericardial effusion), total CT score may have prognostic and therapeutic implication in COVID-19 patients.

Keywords: COVID-19; Chest CT; Echocardiography; Pericardial effusion; Systolic PAP; Total CT score.

MeSH terms

  • Blood Pressure / physiology
  • COVID-19 / mortality
  • COVID-19 / physiopathology*
  • Disease Progression
  • Echocardiography*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pericardial Effusion / diagnostic imaging*
  • Pericardial Effusion / physiopathology
  • Severity of Illness Index
  • Stroke Volume / physiology
  • Ventricular Dysfunction, Left / diagnostic imaging*
  • Ventricular Dysfunction, Left / physiopathology