Case Report of Remifentanil Labor Analgesia for a Pregnant Patient With Congenital Methemoglobinemia Type 1

A A Pract. 2021 Jan 6;15(1):e01373. doi: 10.1213/XAA.0000000000001373.

Abstract

Congenital methemoglobinemia is a rare disease characterized by cyanosis and a left shifting of the oxyhemoglobin dissociation curve. The disease necessitates avoidance of certain medications commonly used in obstetrics, making labor analgesia and anesthesia challenging. We present a case report of peripartum anesthetic management of a pregnant patient with congenital methemoglobinemia type 1 who received remifentanil labor analgesia and continuous methemoglobin monitoring. Continuous real-time monitoring of methemoglobin concentrations may prove to be a useful monitor in future care settings. A review of literature encompassing various perioperative and obstetric anesthesia and analgesia management considerations is presented.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Analgesia*
  • Anesthesia, Obstetrical*
  • Female
  • Humans
  • Methemoglobinemia* / chemically induced
  • Methemoglobinemia* / congenital
  • Methemoglobinemia* / drug therapy
  • Pregnancy
  • Remifentanil

Substances

  • Remifentanil

Supplementary concepts

  • Congenital Methemoglobinemia