Cases: Three patients with knee-level complex regional pain syndrome type 1 (CRPS1), recalcitrant to conservative interventions, elected for transfemoral amputation and osseointegration. Two patients gained independent ambulation; the third remains on crutches after a disrupted sciatic nerve targeted reinnervation. One uses no pain medication, one is weaning off, and one requires a reduced regimen after revision nerve innervation.
Conclusion: Osseointegration seems suitable to optimize rehabilitation after amputation for CRPS1.
Copyright © 2021 The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated.