Electrochemical impedimetric biosensors, featuring the use of Room Temperature Ionic Liquids (RTILs): Special focus on non-faradaic sensing

Sayali Upasham; Ivneet Kaur Banga; Badrinath Jagannath; Anirban Paul; Kai-Chun Lin; Sriram Muthukumar; Shalini Prasad

doi:10.1016/j.bios.2020.112940

Electrochemical impedimetric biosensors, featuring the use of Room Temperature Ionic Liquids (RTILs): Special focus on non-faradaic sensing

Biosens Bioelectron. 2021 Apr 1:177:112940. doi: 10.1016/j.bios.2020.112940. Epub 2020 Dec 30.

Authors

Sayali Upasham¹, Ivneet Kaur Banga², Badrinath Jagannath³, Anirban Paul⁴, Kai-Chun Lin⁵, Sriram Muthukumar⁶, Shalini Prasad⁷

Affiliations

¹ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: Sayali.Upasham@utdallas.edu.
² Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: IvneetKaur.Banga@utdallas.edu.
³ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: bxj160030@utdallas.edu.
⁴ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: anirban.paul@utdallas.edu.
⁵ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: Kai-Chun.Lin@utdallas.edu.
⁶ Enlisense LLC, Allen, TX, USA. Electronic address: sriramm@enlisense.com.
⁷ Department of Bioengineering, University of Texas at Dallas, Richardson, TX, 75080, USA. Electronic address: shalini.prasad@utdallas.edu.

PMID: 33444897
DOI: 10.1016/j.bios.2020.112940

Abstract

Over the last decade, significant advancements have been made in the field of biosensing technology. With the rising demand for personalized healthcare and health management tools, electrochemical sensors are proving to be reliable solutions; specifically, impedimetric sensors are gaining considerable attention primarily due to their ability to perform label-free sensing. The novel approach of using Room Temperature Ionic Liquids (RTILs) to improve the sensitivity and stability of these detection systems makes long-term continuous sensing feasible towards a wide range of sensing applications, predominantly biosensing. Through this review, we aim to provide an update on current scientific progress in using impedimetric biosensing combined with RTILs for the development of sensitive biosensing platforms. This review also summarizes the latest trends in the field of biosensing and provides an update on the current challenges that remain unsolved.

Keywords: Biosensing; Electrochemical; Impedimetric; RTIL.

Publication types

Review

MeSH terms

Biosensing Techniques*
Ionic Liquids*
Temperature

Substances

Ionic Liquids