HOW Collaborative position paper on the management of thrombocytopenia in pregnancy

Aust N Z J Obstet Gynaecol. 2021 Apr;61(2):195-204. doi: 10.1111/ajo.13303. Epub 2021 Jan 12.

Abstract

Thrombocytopenia in pregnancy is a common occurrence, affecting up to 10% of women by the time of birth. These recommendations aim to provide pragmatic guidance on the investigation, diagnosis and management of thrombocytopenia in pregnancy; including safety of neuraxial anaesthesia and precautions required for birth. Management of neonatal thrombocytopenia is also addressed. The authors are clinicians representing haematology, obstetric medicine, maternal-fetal medicine, and anaesthesia. Each author conducted a detailed literature review then worked collaboratively to produce a series of unanimous recommendations. The recommendation strength is limited by the lack of high-quality clinical trial data, and represents level C evidence.

Keywords: pregnancy; thrombocytopenia.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Infant, Newborn
  • Parturition*
  • Pregnancy
  • Thrombocytopenia* / diagnosis
  • Thrombocytopenia* / therapy