Retrospect: The Outbreak Evaluation of COVID-19 in Wuhan District of China

Healthcare (Basel). 2021 Jan 8;9(1):61. doi: 10.3390/healthcare9010061.

Abstract

There were 27 novel coronavirus pneumonia cases found in Wuhan, China in December 2019, named as 2019-nCoV temporarily and COVID-19 formally by the World Health Organization (WHO) on the 11 February 2020. In December 2019 and January 2020, COVID-19 has spread on a large scale among the population, which brought terrible disaster to the life and property of the Chinese people. In this paper, we analyze the features and pattern of the virus transmission. Considering the influence of indirect transmission, a conscious-based Susceptible-Exposed-Infective-Recovered (SEIR) (C-SEIR) model is proposed, and the difference equation is used to establish the model. We simulated the C-SEIR model and key important parameters. The results show that (1) increasing people's awareness of the virus can effectively reduce the spread of the virus; (2) as the capability and possibility of indirect infection increases, the proportion of people being infected will also increase; (3) the increased cure rate can effectively reduce the number of infected people. Then, the virus transmission can be modelled and used for the inflexion and extinction period of pandemic development so as to provide theoretical support for the Chinese government in the decision-making of pandemic prevention and recovery of economic production. Further, this study has demonstrated the effectiveness of the prevention measures taken by the Chinese government such as multi-level administrative district isolation and public health awareness.

Keywords: C-SEIR; COVID-19; infection data; prevention measures.