Therapeutic potential of insulin-like growth factor 2 in Huntington's disease: controlling proteostasis to alleviate the load of misfolded protein

Affiliations

• ¹ Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile; Center for Geroscience, Brain Health and Metabolism; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago; Center for Integrative Biology, Faculty of Sciences, University Mayor, Chile.
• ² Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile; Center for Geroscience, Brain Health and Metabolism; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA.
• ³ Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile; Center for Geroscience, Brain Health and Metabolism, Santiago; Center for Integrative Biology, Faculty of Sciences, University Mayor, Chile.