LRRK2 Loss-of-Function Variants in Patients with Rare Diseases: No Evidence for a Phenotypic Impact

Affiliations

• ¹ CENTOGENE GmbH, Rostock, Germany.
• ² Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.
• ³ National Genetic Center, Royal Hospital, Muscat, Oman.
• ⁴ Neurogenetics Program, AUBMC Special Kids Clinic and Division of Pediatric Neurology, Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
• ⁵ Department of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Beirut, Lebanon.
• ⁶ Genetics and Precision Medicine Department, King Abdullah Specialist Children Hospital, King Abdulaziz Medical City, MNGHA, Riyadh, Saudi Arabia.
• ⁷ King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for Health Sciences, MNGHA, Riyadh, Saudi Arabia.
• ⁸ Department of Medical Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
• ⁹ College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
• ¹⁰ University of Rostock, Medical Faculty, Rostock, Germany.