Relevance of Heparan Sulfate and Heparanase to Severity of COVID-19 in the Elderly

MeSH terms

• Aged, 80 and over / physiology*
• Aging / immunology
• Aging / metabolism*
• Air Pollution / adverse effects
• Animals
• COVID-19 / blood
• COVID-19 / complications
• COVID-19 / metabolism*
• COVID-19 / mortality
• Cadmium / toxicity
• Cytokine Release Syndrome / etiology
• Cytokine Release Syndrome / metabolism
• Disease Models, Animal
• Disease Susceptibility
• Endothelium, Vascular / metabolism
• Endothelium, Vascular / pathology
• Endothelium, Vascular / physiopathology*
• Environmental Pollutants / toxicity
• Female
• Gene Expression Regulation, Enzymologic
• Glucuronidase / biosynthesis
• Glucuronidase / genetics
• Glucuronidase / physiology*
• Glycosaminoglycans / metabolism
• Heparitin Sulfate / metabolism*
• Humans
• Lung / metabolism
• Lung / pathology
• Male
• Prognosis
• Pulmonary Embolism / etiology
• Pulmonary Embolism / mortality
• SARS-CoV-2*
• Venous Thromboembolism / etiology*
• Venous Thromboembolism / mortality
• Venous Thrombosis / etiology
• Venous Thrombosis / mortality