Devic's neuromyelitis optica associated with active pulmonary tuberculosis, Tunisia

S Zayet; A Zaghdoudi; H Harrabi; A Goubantini; H Tiouiri Benaissa

doi:10.1016/j.nmni.2020.100828

Devic's neuromyelitis optica associated with active pulmonary tuberculosis, Tunisia

New Microbes New Infect. 2020 Dec 1:39:100828. doi: 10.1016/j.nmni.2020.100828. eCollection 2021 Jan.

Authors

S Zayet¹, A Zaghdoudi¹, H Harrabi^{1

2}, A Goubantini^{1

2}, H Tiouiri Benaissa^{1

2}

Affiliations

¹ Infectious Diseases Department, Hopital La Rabta, Tunis, Tunisia.
² University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

Abstract

Devic's Optic neuromyelitis (OND) is a very rare disease defined as a central nervous system (CNS) inflammation resulting in optic neuritis and/or myelitis. The discovery of a highly specific serum autoantibody biomarker for the diagnosis has triggered a great interest in conducting further research into this disease. The association of OND with Tuberculosis (TB) is even rarer and could be an entirely random conjunction. To our knowledge, we reported the first case of Neuromyelitis Optica associated with pulmonary TB in Tunisia.

Keywords: Devic's Syndrome; Neuromyelitis Optica; Tunisia; demyelination; tuberculosis.