Necropsy protocol for newborn mice

Lab Anim. 2021 Aug;55(4):358-362. doi: 10.1177/0023677220983374. Epub 2021 Jan 10.

Abstract

Neonatal mortality is high in laboratory mouse breeding, and causes are poorly understood. Post-mortem analysis of pups is an often overlooked source of information and insight. We present a necropsy protocol for neonatal mice designed for easy practical application by animal technicians.

Keywords: Perinatal mortality; mouse; necropsy; pathology; physiology.

MeSH terms

  • Animals
  • Animals, Newborn*
  • Autopsy
  • Mice