Putting the pressure on endocytosis in the kidney

Dorien Van Giel; Rudi Vennekens

doi:10.1016/j.ceca.2020.102338

Putting the pressure on endocytosis in the kidney

Cell Calcium. 2021 Mar:94:102338. doi: 10.1016/j.ceca.2020.102338. Epub 2020 Dec 26.

Authors

Dorien Van Giel¹, Rudi Vennekens²

Affiliations

¹ Laboratory of Ion Channel Research, TRP Research Platform Leuven, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Belgium.
² Laboratory of Ion Channel Research, TRP Research Platform Leuven, VIB Center for Brain and Disease Research, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Belgium. Electronic address: rudi.vennekens@kuleuven.be.

PMID: 33418312
DOI: 10.1016/j.ceca.2020.102338

Abstract

In Science Signaling, Gualdani and colleagues provide evidence that the ion channel TRPV4 functions as a mechanosensor in the renal proximal tubules and show that TRPV4 activity modulates protein reabsorption.

Keywords: Calcium signaling; Cell physiology; Ion channels; Renal physiology.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Albumins
Endocytosis
Kidney Tubules, Proximal*
TRPV Cation Channels*

Substances

Albumins
TRPV Cation Channels