A Versatile eIF3d in Translational Control of Stress Adaptation

Longfei Jia; Shu-Bing Qian

doi:10.1016/j.molcel.2020.12.016

A Versatile eIF3d in Translational Control of Stress Adaptation

Mol Cell. 2021 Jan 7;81(1):10-12. doi: 10.1016/j.molcel.2020.12.016.

Authors

Longfei Jia¹, Shu-Bing Qian²

Affiliations

¹ Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
² Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA. Electronic address: sq38@cornell.edu.

PMID: 33417853
DOI: 10.1016/j.molcel.2020.12.016

Abstract

Lamper et al. (2020) reported that eIF3d-mediated cap-dependent translation is subject to regulation by phosphorylation during chronic glucose deprivation, providing a mechanism underlying selective translation of stress genes essential for cell survival.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Adaptation, Physiological / genetics
Cell Survival
Eukaryotic Initiation Factor-3* / genetics
Eukaryotic Initiation Factor-3* / metabolism
Phosphorylation
Stress, Physiological*

Substances

Eukaryotic Initiation Factor-3

Abstract

Publication types

MeSH terms

Substances

Grants and funding