Mutation Profile of SARS-CoV-2 Genome Sequences Originating from Eight Israeli Patient Isolates

Galia Zaide; Inbar Cohen-Gihon; Ofir Israeli; Dana Stein; Ohad Shifman; Shay Weiss; Irit Simon; Orly Laskar; Adi Beth-Din; Anat Zvi

doi:10.1128/MRA.01387-20

Mutation Profile of SARS-CoV-2 Genome Sequences Originating from Eight Israeli Patient Isolates

Microbiol Resour Announc. 2021 Jan 7;10(1):e01387-20. doi: 10.1128/MRA.01387-20.

Authors

Affiliations

¹ Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel galiaz@iibr.gov.il.
² Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel.
³ Department of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel.
⁴ Department of Biotechnology, Israel Institute for Biological Research, Ness-Ziona, Israel.

Abstract

We report the genome sequences and the identification of genetic variations in eight clinical samples of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Samples were collected from nasopharyngeal swabs of symptomatic and asymptomatic individuals from five care homes for elderly and infirm persons in Israel. The sequences obtained are valuable, as they carry a newly reported nonsynonymous substitution located within the nucleoprotein open reading frame.