Whole-Genome Sequencing of Two Moroccan Mycobacterium tuberculosis Strains

M Laamarti; N El Mrimar; T Alouane; S Kartti; E Belouad; F Bssaibis; A Zegmout; R El Jaoudi; A Maleb; A Abid; N El Hajjami; A Lemnouer; S Siah; L Belyamani; M Elouennass; A Ibrahimi

doi:10.1128/MRA.00635-20

Whole-Genome Sequencing of Two Moroccan Mycobacterium tuberculosis Strains

Microbiol Resour Announc. 2021 Jan 7;10(1):e00635-20. doi: 10.1128/MRA.00635-20.

Authors

M Laamarti¹, N El Mrimar², T Alouane¹, S Kartti¹, E Belouad², F Bssaibis², A Zegmout³, R El Jaoudi¹, A Maleb⁴, A Abid³, N El Hajjami⁵, A Lemnouer², S Siah⁶, L Belyamani⁷, M Elouennass², A Ibrahimi¹

Affiliations

¹ Biotechnology Lab (MedBiotech Center), Rabat Medical and Pharmacy School, University Mohammed V, Rabat, Morocco.
² Department of Bacteriology, Mohammed V Military Teaching Hospital/Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
³ Pneumology Department, Mohammed V Military Teaching Hospital/Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
⁴ Laboratory of Microbiology, Mohammed VI University Hospital/Faculty of Medicine and Pharmacy, University Mohammed the First, Oujda, Morocco.
⁵ Biotechnology Lab (MedBiotech Center), Rabat Medical and Pharmacy School, University Mohammed V, Rabat, Morocco nargisse.el-hajjami@merckgroup.com.
⁶ Department of Burns, Mohammed V Military Teaching Hospital/Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
⁷ Emergency Department, Mohammed V Military Teaching Hospital/Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.

Abstract

Mycobacterium tuberculosis is known to cause pulmonary and extrapulmonary tuberculosis. In Morocco, the spread of multidrug-resistant (MDR) tuberculosis (TB) has become a major challenge. Here, we announce the draft genome sequences of two Mycobacterium tuberculosis strains, MTB1 and MTB2, isolated from patients with pulmonary tuberculosis in Morocco, to describe variants associated with drug resistance.