Risk Associated with the Use of Selected Ingredients in Food Supplements

Chem Biodivers. 2021 Feb;18(2):e2000686. doi: 10.1002/cbdv.202000686. Epub 2021 Jan 21.

Abstract

This review focuses on four new product categories of food supplements: pre-workout, fat burner/thermogenic, brain/cognitive booster, and hormone/testosterone booster. Many food supplements have been shown to be contaminated with unauthorized substances. In some cases, the ingredients in the new categories of dietary supplements were medicinal products or new synthetic compounds added without performing clinical trials. Some of the new ingredients in dietary supplements are plant materials that are registered in the pharmacopoeia as herbal medicines. In other cases, dietary supplements may contain plant materials that have no history of human use and are often used as materials to 'camouflage' stimulants. In the European Union, new ingredients of dietary supplements, according to European Food Safety Authority or unauthorized novel food. Furthermore, selected ingredients in dietary supplements may be prohibited in sports and are recognized as doping agents by World Anti-Doping Agency.

Keywords: SARM; doping, food supplements; new components; steroids; stimulants; toxicology.

Publication types

  • Review

MeSH terms

  • Animals
  • Dietary Supplements / adverse effects*
  • Dietary Supplements / analysis*
  • Doping in Sports
  • Drug Contamination
  • Humans
  • Medicine, Traditional / adverse effects
  • Plant Preparations / adverse effects*
  • Plant Preparations / analysis*
  • Risk

Substances

  • Plant Preparations