mSphere of Influence: Turning to Soil for Medicines

Ching-Hsuan Lin

doi:10.1128/mSphere.01258-20

mSphere of Influence: Turning to Soil for Medicines

mSphere. 2021 Jan 6;6(1):e01258-20. doi: 10.1128/mSphere.01258-20.

Author

Ching-Hsuan Lin¹

Affiliation

¹ Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan chinghsuanlin@ntu.edu.tw.

Abstract

Ching-Hsuan Lin works in the field of Candida biology. In this mSphere of Influence article, he reflects on how the papers "Use of ichip for high-throughput in situ cultivation of uncultivable microbial species" by D. Nichols, N. Cahoon, E. M. Trakhtenberg, L. Pham, et al. (Appl Environ Microbiol 76:2445-2450, 2010, https://doi.org/10.1128/AEM.01754-09) and "A new antibiotic kills pathogens without detectable resistance" by L. L. Ling, T. Schneider, A. J. Peoples, A. L. Spoering, et al. (Nature 517:455-459, 2015, https://doi.org/10.1038/nature14098) made an impact on him by inspiring him to explore new bioactive antimicrobial compounds with his collaborators.

Keywords: antimicrobial compounds; iChip; new antibiotic; uncultivable microorganisms.

MeSH terms

Antifungal Agents / analysis
Antifungal Agents / isolation & purification*
Candida / drug effects
Drug Discovery / methods*
Fungi / drug effects
Humans
Male
Narration
Soil / chemistry*

Substances

Antifungal Agents
Soil