Efficacy of inspiratory muscle training on inspiratory muscle function, functional capacity, and quality of life in patients with asthma: A randomized controlled trial

Clin Rehabil. 2021 Jun;35(6):870-881. doi: 10.1177/0269215520984047. Epub 2021 Jan 6.

Abstract

Objective: To evaluate the efficacy of an inspiratory muscle training protocol on inspiratory muscle function, functional capacity, and quality of life in patients with asthma.

Design: A single-blind, randomized controlled clinical trial.

Setting: Community-based.

Subjects: Patients with asthma, aged between 20 and 70 years old, non-smokers.

Interventions: Participants were randomized into two groups: inspiratory muscle training group performed inspiratory muscle training 5 days a week for 8 weeks, consisting of six sets of 30 breaths per day with a training load ⩾50% of maximal inspiratory pressure, plus an educational program; the control group only received the educational program.

Main measurements: Maximal inspiratory pressure, inspiratory muscle endurance, and the distance performed on the incremental shuttle walking test were assessed pre-intervention, post-intervention and at follow-up (3 months after the end of the intervention). The asthma quality of life questionnaire was applied pre and post-intervention.

Results: Data from 39 participants were analyzed. Maximal inspiratory pressure in percentage of predicted and endurance test duration were significantly higher post-intervention in the inspiratory muscle training group (∆ post-pre: 50.8% vs 7.3% of predicted - P < 0.001 and ∆ post-pre: 207.9 seconds vs 2.7 seconds - P < 0.001, respectively). There was no significant difference in the incremental shuttle walking distance between groups (∆ post-pre: 30.9 m vs -8.1 m, P = 0.165). Quality of life was perceived as significantly better, without a difference between groups (P > 0.05).

Conclusions: About 8 weeks of inspiratory muscle training in patients with controlled asthma significantly increased inspiratory muscle strength and endurance.

Keywords: Inspiratory muscle training; asthma; patient education; rehabilitation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Asthma / rehabilitation*
  • Breathing Exercises / methods*
  • Female
  • Humans
  • Male
  • Maximal Respiratory Pressures / methods
  • Middle Aged
  • Muscle Strength / physiology
  • Quality of Life*
  • Resistance Training / methods*
  • Respiratory Muscles / physiopathology
  • Single-Blind Method