Prevalence, Risk Factors, and Short-Term Outcomes of Full-Term Low Birth Weight Infants Born at a Tertiary Academic Center: A Prospective Case-Control Study

Am J Perinatol. 2022 Sep;39(12):1362-1366. doi: 10.1055/s-0040-1722599. Epub 2021 Jan 6.

Abstract

Objective: Low birth weight (LBW) infants (<2,500 g) continued to be a global health problem because of the associated short- and long-term adverse outcomes. The study aimed to determine the prevalence, risk factors, and short-term outcomes of term LBW infants STUDY DESIGN: A prospective and case-control study. All infants born consecutively from September 1, 2018 to August 31, 2019 were included. Cases, term LBW infants, were 1:1 matched to controls, appropriate for gestational age (AGA) term infants. Major congenital or chromosomal anomalies and multiple pregnancies were excluded.

Results: The prevalence of term LBW in the studied period was 4.8%. Mothers of term LBW infants had significantly lower body mass index (p = 0.05), gained less weight (p = 0.01), had a history of previous LBW (p = 0.01), and lower monthly income (p = 0.04) compared with mothers of term AGA infants even after adjustment for confounders. A nonsignificant higher number of term LBW infants needed NICU admission, while their need for phototherapy was deemed significant.

Conclusion: We identified nutritional and socioeconomic maternal factors that are significantly associated with LBW infants and should be targeted during antenatal visits to improve neonatal outcomes.

Key points: · LBW infants (<2,500 g) are at risk of short- and long-term morbidities.. · Poor maternal nutritional and socioeconomic factors increase the risk of LBW infant.. · Targeting identified risk factors of LBW infant antenatally improve neonatal outcomes.

MeSH terms

  • Birth Weight
  • Case-Control Studies
  • Female
  • Gestational Age
  • Humans
  • Infant
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Pregnancy
  • Prevalence
  • Risk Factors