Abstract
We have developed an in situ bioprinting method that allows the printing of cells under true physiological conditions by applying self-assembling ultrashort peptides as bioinks. This method avoids cell stressing methods, such as UV-treatment, chemical crosslinking and viscous bioink printing methods. We further demonstrate that different nanomaterials can easily be synthesized or incorporated in the 3D bioprinted peptide scaffolds which opens up the possibility of functionalized 3D scaffolds.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Biocompatible Materials / chemical synthesis
-
Biocompatible Materials / chemistry*
-
Bioprinting*
-
Cells, Cultured
-
Humans
-
Hydrogels / chemical synthesis
-
Hydrogels / chemistry*
-
Molecular Conformation
-
Molecular Dynamics Simulation
-
Particle Size
-
Peptides / chemical synthesis
-
Peptides / chemistry*
-
Printing, Three-Dimensional*
-
RNA / analysis
-
RNA / genetics
-
RNA-Seq
-
Surface Properties
-
Tissue Scaffolds / chemistry*
Substances
-
Biocompatible Materials
-
Hydrogels
-
Peptides
-
RNA