Cerebrovascular assessments to help understand brain-related changes associated with aerobic exercise after stroke

Appl Physiol Nutr Metab. 2021 Apr;46(4):412-415. doi: 10.1139/apnm-2020-0228. Epub 2021 Jan 5.

Abstract

Evidence suggests exercise is "good medicine" after stroke, yet consensus is lacking on the time to initiate, type, exertion level, and duration per session. It remains a challenge to identify outcome measures for stroke-exercise trials that are sufficiently sensitive to intervention parameters. Cerebrovascular assessments, namely cerebral blood flow and intracranial pulsatility, are herein discussed as examples of quantitative brain-specific measures that may be useful to monitor exercise-related brain changes and help to guide stroke rehabilitation interventions. Novelty: Cerebral blood flow and arterial stiffness are potential vascular targets for stroke exercise trials.

Keywords: accident vasculaire cérébral; aerobic exercise training; arterial stiffness; cerebral blood flow; cerebrovascular disease; circulation sanguine cérébrale; entraînement aux exercices d’aérobie; intracranial pulsatility; maladie cérébrovasculaire; pulsatilité intracrânienne; raideur artérielle; stroke.

Publication types

  • Review

MeSH terms

  • Brain / physiopathology*
  • Cerebrovascular Circulation*
  • Exercise*
  • Humans
  • Stroke / physiopathology*
  • Stroke Rehabilitation
  • Vascular Stiffness*