Gastric mucosa-associated lymphoid tissue lymphoma in conjunction with multiple lymphomatous polyposis in the context of Helicobacter pylori and Helicobacter suis superinfection

Clin J Gastroenterol. 2021 Apr;14(2):478-483. doi: 10.1007/s12328-020-01310-5. Epub 2021 Jan 4.

Abstract

A 53-year-old woman visited a doctor and complained of chest discomfort after meals. Esophagogastroduodenoscopy showed multiple granular elevations in the gastric body. After biopsies from the elevations, she was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma. Polymerase chain reaction also detected Helicobacter pylori and H. suis. Treatment to eradicate H. pylori and H. suis was successful. Endoscopic examination after the bacterial eradication treatment showed that multiple granular elevations remained in the gastric body; however, no lymphoma cells were found during histopathological examination. Thus, we reported a case of H. pylori-positive gastric MALT lymphoma with a unique morphology associated with H. suis superinfection.

Keywords: Mucosa-associated lymphoid tissue lymphoma; Multiple lymphomatous polyposis; Non-H. pylori helicobacters.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Female
  • Helicobacter Infections* / complications
  • Helicobacter Infections* / drug therapy
  • Helicobacter heilmannii*
  • Helicobacter pylori*
  • Humans
  • Lymphoma, B-Cell, Marginal Zone* / drug therapy
  • Middle Aged
  • Stomach Neoplasms* / drug therapy
  • Superinfection* / drug therapy

Substances

  • Anti-Bacterial Agents