Vermiculite as a new carrier for extracellular protease production by Aspergillus spp. under solid-state fermentation

Alexander A Osmolovskiy; Elizaveta A Popova; Valeriana G Kreyer; Nina A Baranova; Nikolay S Egorov

doi:10.1016/j.btre.2020.e00576

Vermiculite as a new carrier for extracellular protease production by Aspergillus spp. under solid-state fermentation

Biotechnol Rep (Amst). 2020 Dec 16:29:e00576. doi: 10.1016/j.btre.2020.e00576. eCollection 2021 Mar.

Authors

Alexander A Osmolovskiy¹, Elizaveta A Popova¹, Valeriana G Kreyer¹, Nina A Baranova¹, Nikolay S Egorov²

Affiliations

¹ Department of Microbiology, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation.
² International Biotechnological Center, Lomonosov Moscow State University, Moscow, Russian Federation.

Abstract

A new method has been developed to increase the productivity of aspergilli - producers of extracellular proteinases based on their cultivation on vermiculite under solid-state fermentation conditions. The productivity of the mycelium Aspergillus ochraceus L-1 and Aspergillus ustus 1 was 3-18 times higher not only in comparison with submerged cultivation, but also in comparison with growth on other carriers studied under solid-state fermentation conditions. Vermiculite can be considered as a new promising carrier for solid-state fermentation of micromycetes.