Caries arrest effectiveness of silver diamine fluoride compared to alternative restorative technique: randomized clinical trial

Eur Arch Paediatr Dent. 2021 Aug;22(4):575-585. doi: 10.1007/s40368-020-00592-0. Epub 2021 Jan 2.

Abstract

Objective: This RCT study assessed and compared the effect of a biannual application of 38% silver diamine fluoride (SDF) with alternative restorative technique (ART) on arresting caries in primary dentition.

Methods: The RCT was conducted over a period of 12 months and included 79 healthy children (237 primary teeth), aged 3-8 years, selected from the University Pediatric Dentistry outpatient clinics, with at least one primary asymptomatic tooth with active dentinal occlusal/labial lesions. Children were randomly assigned to SDF application or ART treatment. Visual and tactile examinations were used after 6 and 12 months to assess the activity of the carious lesions using the ICDAS II.

Results: At 6- and 12-month-evaluation periods, no statistically significant differences in lesions arrest were found between SDF and ART groups (P = 1.000). Considering the frequency of arrested caries between the test groups at 6 and 12 months, no significant differences were observed between anterior and posterior lesions, as well as between the maxillary and mandibular lesions. When comparing the working time for the two treatments, the median time for those treated with SDF was 3.3 min, compared to 14.4 min for ART and was statistically significant (P < 0.0001).

Conclusion: Both SDF and ART are, indeed, effective for arresting caries. However, the chair-time management required for SDF is significantly shorter compared to ART. Taking into consideration the present evidence, the best decision regarding disease management and application of SDF or ART is to be made by the dentist and the patient/parent, recognizing individuals' differences and preferences.

Keywords: ART; Caries arrest; Primary teeth; Silver diamine fluoride; Working time.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Cariostatic Agents
  • Child
  • Dental Caries Susceptibility*
  • Dental Caries* / drug therapy
  • Dental Caries* / prevention & control
  • Fluorides, Topical
  • Humans
  • Quaternary Ammonium Compounds
  • Silver Compounds

Substances

  • Cariostatic Agents
  • Fluorides, Topical
  • Quaternary Ammonium Compounds
  • Silver Compounds
  • silver diamine fluoride