Fecal microbiota transplantation for membranous nephropathy

CEN Case Rep. 2021 May;10(2):261-264. doi: 10.1007/s13730-020-00560-z. Epub 2021 Jan 2.

Abstract

Membranous nephropathy is a pathological type of nephrotic syndrome. Current treatments including supportive therapy, corticosteroids, immunosuppressive agents are not effective for all patients. New therapies are needed to treat the disease safely and effectively. Gut microbiota may contribute to the pathogenesis of this disease. Fecal microbiota transplantation (FMT) has made achievements in many diseases. Here, we report a case in which FMT is used to treat a patient with membranous nephropathy and chronic diarrhea, whose symptoms ameliorated and renal function improved.

Keywords: Fecal microbiota transplantation; Gut microbiota; Membranous nephropathy.

Publication types

  • Case Reports

MeSH terms

  • Chronic Disease
  • Diarrhea / complications
  • Diarrhea / therapy
  • Fecal Microbiota Transplantation*
  • Glomerulonephritis, Membranous / complications
  • Glomerulonephritis, Membranous / therapy*
  • Humans
  • Treatment Outcome