High-intensity interval training (HIIT) and strength exercise are known to improve health markers, such as cardiovascular health, metabolic health, and cognitive function, as well as to reduce all-cause mortality. High-Intensity Functional Training (HIFT) is a training paradigm derived from both HIIT and strength exercise to elicit greater muscle recruitment than repetitive aerobic exercises, thereby improving both cardiovascular fitness and strength parameters. Herein, we provide a focused review of the known molecular mechanisms that underlie the beneficial effects of HIFT on cardiovascular, metabolic, and cognitive functions.
Keywords: Crossfit®; HIFT; HIIT; Mechanical tension; Resistance training; mTOR.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.