Potential of pulsed light technology for control of SARS-CoV-2 in hospital environments

J Photochem Photobiol B. 2021 Feb:215:112106. doi: 10.1016/j.jphotobiol.2020.112106. Epub 2020 Dec 28.

Abstract

The emergence of the SARS-CoV-2 infection and its potential transmission through touching surfaces in clinical environments have impelled the use of conventional and novel methods of disinfection to prevent its spreading. Among the latter, pulsed light may be an effective, non-chemical decontamination alternative. Pulsed light technology inactivates microorganisms and viruses by using high intensity polychromatic light pulses, which degrades nucleic acids and proteins. This review describes this technology, compiles and critically analyzes the evidence about the virucidal efficacy of pulsed light technology with view on its potential use against SARS-CoV-2 in touching surfaces in health-care facilities. The efficacy of pulsed light proved against many different kind of viruses allows to conclude that is a suitable candidate to inactivate SARS-CoV-2 as long as the required fluence is applied and the appropriated exposure to contaminated surfaces is guaranteed.

Keywords: COVID-19; Disinfection; Hospital-acquired infections; Pulsed light; SARS-CoV-2; Touching surfaces.

Publication types

  • Review

MeSH terms

  • Animals
  • COVID-19 / prevention & control*
  • COVID-19 / transmission
  • Hospitals
  • Humans
  • Infection Control / methods*
  • Light*
  • SARS-CoV-2 / radiation effects*