Quetiapine and Wolff-Parkinson-White Syndrome

Michael Chen; Hassaan Gomaa; Alonso Cortez-Resendiz; Christopher Martin; Andrew Francis; Alfredo Bellon

doi:10.1155/2020/6633385

Quetiapine and Wolff-Parkinson-White Syndrome

Case Rep Psychiatry. 2020 Dec 11:2020:6633385. doi: 10.1155/2020/6633385. eCollection 2020.

Authors

Michael Chen¹, Hassaan Gomaa², Alonso Cortez-Resendiz², Christopher Martin³, Andrew Francis², Alfredo Bellon^{2

4}

Affiliations

¹ Department of Psychiatry, Lehigh Valley Health Network, 2545 Schoenersville road, Bethlehem PA 18017, USA.
² Department of Psychiatry and Behavioral Health, Penn State Hershey Medical Center, 500 University Drive P.O. Box 850. Mail Code R130. Hershey, PA 17033-0850, USA.
³ Department of Psychiatry, Thomas Jefferson University, Philadelphia, PA, USA.
⁴ Department of Pharmacology, Penn State College of Medicine, Penn State Hershey Medical Center, Hershey, PA, USA.

Abstract

Quetiapine is occasionally associated with cardiovascular adverse effects such as QTc prolongation. QTc prolongation is a side effect that requires monitoring in order to avoid more serious cardiac complications. One particular understudied area is the potential for antipsychotics to elicit electroconduction abnormalities in patients with Wolff-Parkinson-White (WPW) Syndrome. In the present report, we describe a case of quetiapine overdose in a patient with WPW.

Publication types

Case Reports