Radiation-induced neovascular glaucoma: A devastating disease

J Cancer Res Ther. 2020 Dec;16(Supplement):S213-S216. doi: 10.4103/jcrt.JCRT_900_18.

Abstract

Neovascular glaucoma (NVG) is a potentially blinding form of secondary glaucoma, with radiation being one of the rare causes. This report is aimed to discuss a case of NVG caused secondary to radiotherapy (RT) given for a nasal malignancy. A 50-year-old male presented with enophthalmos, dry eye, and NVG 3 years after receiving RT for chondrosarcoma of nasal and paranasal cavities. He was given topical antiglaucoma medications, retinal laser, and intravitreal bevacizumab injection and thus prevented the eye from becoming a painful blind eye. The radiation oncologist and ear, nose, and throat specialists have to liaise closely with ophthalmologist when patients receive radiation involving the eye in the treatment field to prevent, diagnose, and treat this devastating condition.

Keywords: Neovascular glaucoma; ophthalmic complications of radiotherapy; radiation.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms / pathology
  • Bone Neoplasms / radiotherapy*
  • Chondrosarcoma / pathology
  • Chondrosarcoma / radiotherapy*
  • Glaucoma, Neovascular / etiology
  • Glaucoma, Neovascular / pathology*
  • Humans
  • Male
  • Middle Aged
  • Nose Neoplasms / pathology
  • Nose Neoplasms / radiotherapy*
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / radiotherapy*
  • Prognosis
  • Radiotherapy / adverse effects*