Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature

Majd Akbik; Dima Naddeh; Anas A Ashour; Azzam Ashour

doi:10.2147/IMCRJ.S286335

Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature

Int Med Case Rep J. 2020 Dec 15:13:697-699. doi: 10.2147/IMCRJ.S286335. eCollection 2020.

Authors

Majd Akbik¹, Dima Naddeh², Anas A Ashour^{3

4}, Azzam Ashour¹

Affiliations

¹ Al-Thumama Health Center, Primary Health Care Corporation, Doha 26555, Qatar.
² Muaither Health Center, Primary Health Care Corporation, Doha 26555, Qatar.
³ College of Medicine, QU Health, Qatar University, Doha 2713, Qatar.
⁴ Medical Education, Hamad Medical Corporation, Doha 3050, Qatar.

Abstract

Immune thrombocytopenia (ITP) is an autoimmune disease that occurs following viral illnesses and may also infrequently occur after measles, mumps, and rubella (MMR) vaccination. ITP typically presents with the sudden appearance of a petechial rash, bruising, and/or bleeding in an otherwise healthy-appearing child. However, ITP following MMR vaccine does not commonly cause severely depleted platelets. We report a case of ITP after MMR vaccination in a 13-month-old baby boy, who presented with petechial rash all over his body. The child had severe thrombocytopenia but was successfully treated with a single dose of intravenous immunoglobulin without complications. The study highlights that ITP post-MMR vaccine is an easily treatable condition.

Keywords: MMR vaccine; case report; immune thrombocytopenia; thrombocytopenia.

Publication types

Case Reports